Fast Facts:

About: QWO is the first and only FDA approved injectable butt cellulite treatment, designed for moderate to severe cellulite dimpling in women’s buttocks. Due to its one of a kind injectable nature, QWO has become the gold standard for cellulite elimination.

Safety: QWO is FDA approved as a safe and effective method to permanently eliminate cellulite in the female buttocks. There are limited risks and side effects, which are temporary and will not affect the outcome of the treatment.

Convenience: A single session of this injectable takes no longer than 30 minutes. In addition, there is zero downtime, allowing patients to return to normal daily activities immediately after treatment.

Cost: The average cost of QWO ranges $1000 – $3000 per 1 session.

Efficacy: Scientific studies have conclusively demonstrated QWO to be effective in reducing and permanently eliminating cellulite.

Contents

WHAT IS CELLULITE?

Cellulite is a complex multifactorial condition particularly prevalent in postpubertal women in areas of the lower body where fat accumulation is especially present such as the buttocks, abdomen and thighs. In fact, 90% of women are affected by this condition, regardless of their size or weight. Cellulite can be found in people of any gender, age, size, and background, and can be not only incredibly frustrating, but very difficult to get rid of.

The causes behind cellulite are diverse and can be due to hormonal factors, genetics, age, weight, underlying medical conditions, low-grade inflammation, and sometimes even diet.

Cellulite makes its appearance when fat pockets below the skin herniate, leaving you with lumpy dimples visible above the surface layer of the skin. Fibrous collagen-rich septae play a key role in the pathophysiology of cellulite and are a major contributing factor to the appearance of cellulite dimples. They are narrow fibrous bands that run vertically between the surface of the skin and the underlying tissues of the fascia. When these collagen bands are too short, they pull the skin downward to deeper tissue levels, creating classic cellulite dimpling and “orange peel” or “cottage cheese-like” skin texture.

Cellulite can be compared to a mattress, as mattresses tend to have indents where the outer surface is anchored into the center of the mattress. Similarly, fibrous septae are anchoring the skin to deeper tissues, causing cellulite dimpling.

cellulite treatment

WHAT ARE DIFFERENT GRADES OF CELLULITE?

A study conducted by the Journal of European Academy of Dermatology and Venerology recognized three grades, or types of cellulite including grade 1, mild superficial dimpling with 1 – 4 slight depressions in the skin, grade 2, moderate deeper rippling of the skin with 5 – 9 medium depressions in the skin, and grade 3, severe deep rippling of the skin with 10 or more deep depressions. While grade 2 and grade 3 cellulite are more visible, all grades of cellulite can be frustrating, especially if you have tried everything to minimize its appearance.

WHY DO I HAVE CELLULITE?

While the exact cause of cellulite is not fully determined, studies indicate that connective tissue and fat are the primary underlying factors as the fat cells protrude in between these connective tissues causing unattractive lumps and dimpling.

Hormones may also play a role in the development of these pesky dimples, such as thyroid hormones, prolactin, noradrenaline, insulin, particularly in menopausal women as estrogen and collagen shift within the connective tissue. Diet and lifestyle may also contribute to cellulite, as enlarged fat cells are more likely to protrude outward.

WHAT IS THE NEW CELLULITE TREATMENT QWO?

Comprised of Collagenase Clostridium Histolyticum (CCH), QWO is the most effective new cellulite treatment using injectable medicine designed to break down collagen strands that make up the fibrous septae under the skin, using two active enzymes, AUX-I and AUX-II. These enzymes break down fibrous bands, releasing pulling tension on the dermis and allowing the skin to become smooth and less dimply. You can expect to see results after just three sessions spaced 21 days apart with no downtime whatsoever.

WHY IS QWO CELLULITE TREATMENT SO POPULAR?

Cellulite is a condition that affects 9 out of 10 women, causing orange peel-like dimpling in the buttocks, thighs, arms, and abdomen, taking a major toll on one’s self confidence. While it is more prevalent in women, cellulite affects men as well, and unfortunately, is incredibly difficult to treat. A major misconception is that cellulite is caused by poor diet and lack of exercise, however, several studies have found that cellulite is primarily the result of genetics and hormonal factors.

In the past, the best methods to treat cellulite included mechanical and laser devices, such as Cellfina and Cellulaze, both of which work to break down fibrous septae by inserting surgical tools below the skin through an incision. This can become uncomfortable and requires a lengthy recovery due to the invasiveness of the procedures.

While there are some non-invasive options to help reduce the appearance of these unappealing dimples, such as creams and lotions, the results are always temporary and unfortunately, barely noticeable.

Endo Aesthetics came up with a solution that allows for a minimally invasive and effective alternative to the above mentioned options, which permanently eliminates cellulite: QWO. QWO is a one of a kind injectable treatment which breaks down fibrous septae upon injection, releasing the dimples and leaving smooth, unaffected skin behind. The treatment requires no surgery and no downtime and is a comfortable and quick procedure with limited side effects. It is no wonder that so many patients are raving about QWO, as it is the only injectable permanent solution to get rid of cellulite dimpling once and for all.

HOW DOES QWO WORK TO REDUCE CELLULITE?

This innovative procedure for cellulite removal works by targeting fibrous septae, the bands that create tension between fat, fascia, and dermis, making them the main cause behind cellulite dimpling. An active enzyme called collagenase clostridrium histolyricum-aaes is injected directly into the cellulite dimple, where fibrous septae are located. This initiates enzymatic subcision and remodeling, also called ESR, a process in which cellulite-causing collagen molecules are broken down through the release of enzymes (AUX-I and AUX-II) targeting collagen types 1 and 3. The septae and associated tethering effects are released and collagen is stimulated (neocollagenesis) resulting in firmer and smoother skin.

WHAT IS ENZYMATIC SUBCISION AND REMODELING?

Enzymatic Subcision and Remodeling (ESR) is the mechanism of action of QWO injections in which collagen-rich fibrous septae are broken down by enzymes within the formulation. When injected into the area beneath a dimple, QWO cellulite treatment disrupts these subdermal fibrous structures, allowing the dermis to release and become smoother without the dimpling associated with cellulite.

WHAT AREAS CAN BE TREATED BY QWO?

QWO is currently only FDA-approved to reduce cellulite in the buttocks of women. Off-label injections into thighs are also currently being done by highly skilled doctors.

WHO IS A CANDIDATE FOR INJECTABLE CELLULITE ELIMINATION?

Cellulite is present in both men and women. However, as of now, QWO is only FDA-approved to treat cellulite in the buttocks of women. If you are a woman experiencing true, well-defined cellulite-related dimpling in the buttocks, you may be a great candidate for this injectable solution.

The best way to find out whether you are a good candidate for QWO is to consult with Dr. Schwarzburg, who is a board certified expert in evaluating cellulite and recommending the best treatment plan for you to accomplish your goals.

HOW DO I PREPARE FOR QWO INJECTIONS?

Before you go in for your injections, it is important to have a consultation with Dr. Schwarzburg to confirm that you are a good candidate for QWO. Before your actual appointment, you will be advised not to take any blood thinners, and refrain from drinking and smoking 2 – 3 days prior to your treatment. You may take 2 Tylenols one hour before the injection process to minimize discomfort, though the treatment is typically not painful at all.

WHAT IS A QWO PROCEDURE LIKE?

  • Consultation:
    If you are interested in reducing and eliminating that stubborn cellulite, the process is fairly quick and simple. Before being scheduled for the treatment, you will meet with Dr. Schwarzburg for a one on one consultation as an opportunity to discuss your problem areas, concerns, the treatment itself, and whether or not you are a candidate for it.
  • How is QWO administered?
    If you are a candidate, Dr. Schwarzburg will develop a tailored treatment plan that will cater to your individual goals, needs and body. During the treatment, Dr. Schwarzburg will sanitize and mark the treatment area for ideal injection placement, and carefully inject QWO into the problem areas using tiny hollow needles. While a topical numbing cream may be applied before the treatment, most patients will not need it as it is typically described as painless. Once the treatment is complete (within 30 minutes), there is no downtime, meaning that the patient can resume with normal activities right after the procedure. There will be moderate to severe bruising and slight swelling in the treatment area lasting up to 2 weeks

HOW LONG DOES A QWO TREATMENT TAKE?

The injection process takes no longer than 30 minutes from start to finish.

ARE THERE ANY RISKS AND SIDE EFFECTS WITH QWO?

The most common reported side effect associated with QWO is bruising. In rare cases there may also be some pain, nodule formation, pruritus, erythema, discoloration, swelling, and warmth around the treatment area, all of which are temporary and treatable. You should not get the treatment if you have a history of hypersensitivity to any collagenase injections for fat loss or to any of the components of the drug  itself, or if you have any kind of infection around the injection site. If you have any history of bleeding abnormalities or are being treated with antiplatelet or anticoagulant therapy, the treatment could result in above average bruising.

IS THERE AFTERCARE OR DOWNTIME AFTER QWO?

Because QWO is non-surgical and consists of tiny injections, it does not require any anesthesia and you can return to normal daily activities immediately after the process.

You will be advised to forgo any strenuous activities for 3 – 5 days after your injections, though there is no true downtime associated with the treatment. In addition, one of the most common major side effects is bruising, which may take up to 2 – 3 weeks to subside.

HOW MUCH DOES QWO COST?

The QWO cellulite treatment cost varies depending on the severity of your cellulite, the number of treatments needed, and the geographical location and qualifications of your provider. On average the QWO cost in NYC ranges $2000 – $4000 for 3 treatment sessions, which is typically the number of sessions needed to treat severe cellulite. Most treatments that reduce the appearance of cellulite require several follow up appointments and will last for up to a year. QWO injections require approximately three sessions that will give you results that are permanent if you maintain a healthy lifestyle and diet.

DOES BODY WEIGHT AFFECT CELLULITE?

The number on the scale itself does not directly cause cellulite, however, dimpling may increase during weight gain or weight loss. While there is a common misconception that cellulite is strictly caused by fatty tissue, it is primarily influenced by genetic factors and hormones, regardless of your size.

IS THE FAT INVOLVED IN CELLULITE THE SAME AS OTHER FAT IN THE BODY?

Research has found that fat cells involved with cellulite are often larger and more metabolically stable than other fat cells in the body. This makes it much harder to reduce the fat that protrudes outward between the fibrous septae, and is also the reason why the condition can be seen in men and women of all shapes and sizes.

WHAT ARE THE MOST COMMON SITES FOR CELLULITE TO APPEAR?

Clinical practices have found that the most common areas in which cellulite tends to develop include the buttocks, thighs, arms, and lower abdomen. However, it may also be present in other areas.

CAN SKINNY PEOPLE GET CELLULITE?

Cellulite can affect anyone, regardless of weight. The main factors that lead to these unflattering dimples include genetics, diet, hormones, age, and activity level.

DO CERTAIN FOODS CAUSE CELLULITE?

There is no particular food that will cause cellulite. However, certain foods higher in calories or fat may increase the chances of weight gain and cellulite.

CAN MEN GET CELLULITE?

Based on evidence found by the American Academy of Dermatology (or AAD) while anyone can be affected by cellulite, women are hormonally more likely to suffer from it than men. Cellulite is often associated with being overweight, however, cellulite can be seen in people of all shapes and sizes in various forms depending on the thickness and elasticity of the skin, one’s genetics, and several additional factors.

WHY IS CELLULITE MORE COMMON IN WOMEN THAN MEN?

Women tend to carry more fat and an increased fat lobule height compared to men, while the fibrous septae in men are stronger and denser than in women. Because there is a thicker web of fibrous septae in men, there is less space for fatty tissue to protrude in between, reducing the irregular skin appearance classically seen in cellulite.

IS CELLULITE PREVENTABLE? HOW CAN I PREVENT MYSELF FROM GETTING CELLULITE?

While maintaining a healthy diet and keeping your body fat percentage at a healthy minimum can benefit you and reduce the chances of developing deep cellulite dimples, unfortunately there aren’t any particularly successful preventative measures that can be taken for cellulite unless it is through a medical treatment, as cellulite is influenced by various uncontrollable factors.

WILL MY CELLULITE IMPROVE IF I LOSE WEIGHT?

The fat present in areas of cellulite formation typically cannot be used as fuel by the body and remains in place regardless of weight loss, exercise, and lifestyle. Losing weight may reduce the appearance of cellulite, but will not address the root of the problem: thick collagen strands.

ARE THERE NATURAL REMEDIES TO GET RID OF CELLULITE?

There is currently no evidence of effective natural remedies to treat cellulite. While natural weight loss may reduce the appearance of dimpling, it will not permanently eliminate it. There are some natural techniques, such as lymphatic drainage massages, which stimulate blood circulation, reducing the appearance of dimples for temporary improvement.

WHO MAKES QWO?

Endo International is an international pharmaceutical company known for urology, men’s health, orthopedics, and endocrinology, branched out with Endo Aesthetics and successfully developed QWO cellulite treatment.

WHAT IS COLLAGENASE?

Collagenase Clostridium Histolyticum (CCH) is an enzyme that breaks down type 1 and type 3 collagen, and is the primary active ingredient in QWO.

IS COLLAGENASE ONLY AVAILABLE IN INJECTION FORM?

Collagenese started out as a topical cream to treat severe burns and skin ulcers and to help remove dead skin tissue, speeding up your body’s natural healing process. However, for cellulite treatment, collagenese is most effective when used as an injectable, as a topical cream will not address fibrous septae below the surface of the skin.

CAN QWO BE COMBINED WITH OTHER TREATMENTS?

QWO is designed to eliminate cellulite in the thighs and buttocks of adult females and is often combined with various body contouring procedures including CoolSculpting and Kybella for non-surgical fat reduction, and EmSculpt and CoolTone to enhance muscle definition in the thighs, buttocks, and abdomen. In addition, Sculptra butt lift  injections can be administered to enhance the size of the buttocks, for an overall smoother “hourglass” look.

ARE LASERS USED TO TREAT CELLULITE?

In some cases laser treatments such as Fraxel can be used for skin tightening in areas such as the abdomen and arms. While Fraxel will not eliminate cellulite, it may make the skin surface appear smoother and minimize the appearance of dimpling.

Cellulaze is a leg cellulite treatments which involves the insertion of a tiny laser beneath the skin that is meant to cut through fibrous septae. While Cellulaze does work, it is invasive and painful with significant downtime.

WHAT IS SCULPTRA AND CAN IT BE USED FOR TREATING CELLULITE?

Sculptra is an injectable solution made of poly-L-lactic acid, used as a dermal filler to create volume in the face and buttocks. There have been some attempts to use dermal fillers to fill in cellulite dimples, though they resulted in little to no success. Fillers for cellulite before and after results are minimal, though they can sometimes help.

CAN LIPOSUCTION BE USED TO TREAT CELLULITE?

Liposuction is used to remove unwanted fat in areas that often are accompanied by cellulite. While fat reduction may help reduce the appearance of cellulite, it is not designed to treat it, which is why liposuction is not ideal to treat dimpling. However, in the process of cutting through adipose tissue during liposuction, it is possible that randomized fibrous septae may be severed, resulting in a reduction of cellulite dimpling.

WHAT IS CELLFINA?

Cellfina is a procedure in which a small hand-held microblade is inserted underneath the skin to cut through fibrous septae causing cellulite. The treatment is invasive and comes with up to two weeks of downtime.

WHAT IS XIAFLEX?

Xiaflex is essentially the same thing as QWO. Both are injectables for cellulite and break down collagen strands that pull the dermis inward creating classic cellulite dimpling. This results in the reduction and elimination of cellulite.

HOW MANY TREATMENTS WILL I NEED?

Clinical trials have shown that the best results are seen after 3 treatment sessions carried out 3 weeks apart from each other. However, results may be seen after just one session as well.

DO QWO INJECTIONS HURT?

The injections themselves are completely painless. Injection site tenderness is possible after your session. Most patients find QWO to be less painful than botox.

HOW LONG UNTIL YOU CAN SEE QWO RESULTS?

You will see the maximum results 28 days after your 3rd treatment. However, you may already see results within 3 weeks after your 1st session.

WHAT WILL MY QWO BEFORE AND AFTER RESULTS LOOK LIKE?

Before your QWO injections you will have a collection of cellulite dimples resistant to diet and exercise in your buttocks and thighs. These dimples may cause insecurity and issues with your self-esteem. Once your results have settled 28 days after your third QWO cellulite treatment, your QWO cellulite before and after results will amaze you. The treated dimples will be permanently eliminated and your thighs and buttocks will be overall smoother in texture and appearance.

HOW LONG WILL MY QWO RESULTS LAST?

Research has demonstrated that QWO results are permanent in the treated areas. However, new cellulite in other areas may develop.

IS IT COVERED BY INSURANCE?

QWO is not a medically necessary treatment and is not covered by insurance.

DOES QWO WORK FOR CELLULITE?

QWO injections were FDA approved to help eliminate cellulite in the buttocks and upper thighs in adult women with moderate to severe cellulite after a study with over 800 participants was conducted resulting in significantly effective outcomes.

IS QWO SAFE TO TREAT CELLULITE?

The FDA approved QWO cellulite treatment in 2020 with Collagenase Clostridium Histolyticumaaes being a new development in the world of cosmetic medicine and dermatology that has been proven to permanently eliminate cellulite in the female buttocks. Mild side effects include bruising and sensitivity in the treatment area, both of which are temporary and do not affect the results of the procedure.

WHAT ARE PROS AND CONS OF CELLULITE INJECTIONS?

Pros:

  • Rigorously studied and found to be both safe and effective
  • FDA approved to treat cellulite in the female buttocks
  • No downtime
  • Virtually painless procedure

Cons:

  • Results are not immediate
  • May require up to 3 sessions for optimal results
  • Primary side effect is severe bruising
  • Does not prevent the formation of new cellulite dimples

TAKEAWAY

QWO is a minimally invasive injectable procedure to treat cellulite by breaking down the fibrous septae beneath the skin, which cause cellulite dimpling. The procedure is FDA approved as a safe and effective method to do so, and involves minimal side effects or downtime. The best results are seen after 3 sessions spaced out by 3 weeks each. Results can be observed within 28 days after the first treatment and improve with each consecutive treatment for permanent cellulite elimination.

HOW CAN I GET STARTED WITH QWO?

If you have been facing issues with cellulite and would like to treat it using QWO injectable treatment, Dr. Schwarzburg is ready to treat you. With a decade of experience in cosmetic medicine, Dr. Schwarzburg is a leading expert in the field and offers a variety of treatments for cellulite reduction in Manhattan at his chic NYC medical spa. To schedule your one on one consultation with Dr. Schwarzburg, please call (212) 774-4264, or email us at info@skinlyaesthetics.com.